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Anti-LFG3/ ™BIM1/ MST100 monoclonal antibody
Anti-LFG3/ ™BIM1/ MST100 antibody for FACS & in-vivo assay
Go to ™BIM1/™BIM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1805-Ab-1/ GM-Tg-hg-MP1805-Ab-2 | Anti-Human ™BIM1 monoclonal antibody | Human |
| GM-Tg-rg-MP1805-Ab-1/ GM-Tg-rg-MP1805-Ab-2 | Anti-Rat ™BIM1 monoclonal antibody | Rat |
| GM-Tg-mg-MP1805-Ab-1/ GM-Tg-mg-MP1805-Ab-2 | Anti-Mouse ™BIM1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1805-Ab-1/ GM-Tg-cynog-MP1805-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ™BIM1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1805-Ab-1/ GM-Tg-felg-MP1805-Ab-2 | Anti-Feline ™BIM1 monoclonal antibody | Feline |
| GM-Tg-cang-MP1805-Ab-1/ GM-Tg-cang-MP1805-Ab-2 | Anti-Canine ™BIM1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1805-Ab-1/ GM-Tg-bovg-MP1805-Ab-2 | Anti-Bovine ™BIM1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1805-Ab-1/ GM-Tg-equg-MP1805-Ab-2 | Anti-Equine ™BIM1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1805-Ab-1/ GM-Tg-hg-MP1805-Ab-2; GM-Tg-rg-MP1805-Ab-1/ GM-Tg-rg-MP1805-Ab-2; GM-Tg-mg-MP1805-Ab-1/ GM-Tg-mg-MP1805-Ab-2; GM-Tg-cynog-MP1805-Ab-1/ GM-Tg-cynog-MP1805-Ab-2; GM-Tg-felg-MP1805-Ab-1/ GM-Tg-felg-MP1805-Ab-2; GM-Tg-cang-MP1805-Ab-1/ GM-Tg-cang-MP1805-Ab-2; GM-Tg-bovg-MP1805-Ab-1/ GM-Tg-bovg-MP1805-Ab-2; GM-Tg-equg-MP1805-Ab-1/ GM-Tg-equg-MP1805-Ab-2 |
| Products Name | Anti-™BIM1 monoclonal antibody |
| Format | mab |
| Target Name | ™BIM1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-™BIM1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species LFG3/ ™BIM1/ MST100 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP003188 | human ™BIM1 Lentivirus plasmid |
| ORF Viral Vector | vGMAD000119 | human ™BIM1 Adenovirus particle |
| ORF Viral Vector | pGMAD000119 | human ™BIM1 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000120 | human ™BIM1 Adenovirus particle |
| ORF Viral Vector | pGMAD000120 | human ™BIM1 Adenovirus plasmid |
| ORF Viral Vector | vGMLP003188 | human ™BIM1 Lentivirus particle |
| ORF Viral Vector | pGMAD000334 | mouse Tmbim1 Adenovirus plasmid |
| ORF Viral Vector | pGMAAV000293 | Norway rat Tmbim1 AAV plasmid |
| ORF Viral Vector | vGMAD000334 | mouse Tmbim1 Adenovirus particle |
| ORF Viral Vector | vGMAAV000293 | Norway rat Tmbim1 AAV particle |
Target information
| Target ID | GM-MP1805 |
| Target Name | ™BIM1 |
| Gene ID | 64114,69660,316516,698325,102153649,101086997,404134,100055634 |
| Gene Symbol and Synonyms | 2310061B02Rik,LFG3,mKIAA4161,MST100,MSTP100,PP1201,RECS1,Tmbib1,™BIM1 |
| Uniprot Accession | Q969X1 |
| Uniprot Entry Name | LFG3_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000135926 |
| Target Classification | N/A |
The target: ™BIM1, gene name: ™BIM1, also named as LFG3, MST100, MSTP100, PP1201, RECS1. Enables death receptor binding activity. Involved in negative regulation of Fas signaling pathway; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of protein localization to plasma membrane. Located in Golgi apparatus; endosome membrane; and lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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