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It's the GeneMedi's summary page for Target/Biomarker Introduction of GOT2. The page also collects GeneMedi's different modalities and formats products for GOT2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GOT2 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

Target IDGM-MP2587
Target NameGOT2
Gene ID2806
Gene Official NameGOT2
Gene AliasKAT4, KATIV, KYAT4, mitAAT
Protein Sub-locationTransmembrane Protein
Categorynull


Pre-made anti-GOT2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-GOT2 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GOT2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Cat No.Antibody NameFormatClassified by tagOrder
GM-Tg-hg-MP2587-AbAnti-GOT2 monoclonal antibodymabBiofunctional antibodymonoclonal antibody.




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