Midkine/MDK: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of Midkine/MDK. The page also collects GeneMedi's different modalities and formats products for Midkine in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the Midkine target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

Target IDGM-T03878
Target NameMidkine
Gene ID4192,17242,81517,714591,119864230,101087941,280852,100147284
Gene Symbol and SynonymsARAP,MDK,Mek,MK,NEGF2
Uniprot AccessionP21741,Q9R1S9
Uniprot Entry NameMK_HUMAN,MK_RAT
Protein Sub-locationSecreted Protein/Potential Cytokines
CategoryTherapeutics Target
DiseaseLung Cancer, Malignant neoplasm of bladder, Urinary bladder urothelial carcinoma, breast cancer
Gene EnsemblENSG00000110492
Target ClassificationN/A


Pre-made anti-Midkine inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-Midkine benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-Midkine mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-Midkine/MDK monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Recombinant multi-species MK/ Midkine/ MDK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Midkine/MDK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
Midkine/MDK proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made MDK viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP000499human MDK Lentivirus particleNM_002391HumanLentivirus particleDetail
vGMAP000446Human MDK Adenovirus particleBC011704HumanAdenovirus particleDetail
pGMAP000446Human MDK Adenovirus plasmidBC011704HumanAdenovirus plasmidDetail
pGMLP000499human MDK Lentivirus plasmidNM_002391HumanLentivirus plasmidDetail
pGMAP000465Human MDK Adenovirus plasmidBC011704HumanAdenovirus plasmidDetail
vGMAP000465Human MDK Adenovirus particleBC011704HumanAdenovirus particleDetail
pGMLPm000134mouse Mdk Lentivirus plasmidNM_010784MouseLentivirus plasmidDetail
vGMLPm000134mouse Mdk Lentivirus particleNM_010784MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






GENEMEDI
Email: [email protected]   [email protected]
Telephone: +86-21-50478399   Fax: 86-21-50478399
Privacy Policy
<