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PROC: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of PROC. The page also collects GeneMedi's different modalities and formats products for PROC in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PROC target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]

Target IDGM-T24836
Target NamePROC
Gene ID5624,19123,25268,699077,476104,101096161,281428,100051306
Gene Symbol and SynonymsAPC,PC,PROC,PROC1,THPH3,THPH4
Uniprot AccessionP04070,P31394,Q28506,Q28278,Q28412,P00745,Q28380
Protein Sub-locationSecreted Protein/Potential Cytokines
CategoryTherapeutics Target
Gene EnsemblENSG00000115718
Target ClassificationTumor-associated antigen (TAA)

Pre-made anti-PROC inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-PROC benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PROC mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-PROC monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail

Recombinant multi-species PROC/ APC/ PC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PROC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
PROC proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail

Pre-made PROC viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLV000878human PROC Lentivirus plasmidNM_000312HumanLentivirus plasmidDetail
vGMLV000878human PROC Lentivirus particleNM_000312HumanLentivirus particleDetail
vGMLP003901human PROC Lentivirus particleBC034377HumanLentivirus particleDetail
vGMLV000573human PROC-mu Lentivirus particleNM_000312HumanLentivirus particleDetail
pGMLV000573human PROC-mu Lentivirus plasmidNM_000312HumanLentivirus plasmidDetail
pGMLP002690human PROC Lentivirus plasmidNM_000312HumanLentivirus plasmidDetail
vGMLP003902human PROC Lentivirus particleNM_000312.3HumanLentivirus particleDetail
pGMLP003902human PROC Lentivirus plasmidNM_000312.3HumanLentivirus plasmidDetail
pGMLP003901human PROC Lentivirus plasmidBC034377HumanLentivirus plasmidDetail
vGMLP002690human PROC Lentivirus particleNM_000312HumanLentivirus particleDetail
pGMLPm004981mouse Proc Lentivirus plasmidNM_008934.4MouseLentivirus plasmidDetail
vGMLPm004981mouse Proc Lentivirus particleNM_008934.4MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.

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