NFKBIA: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of NFKBIA. The page also collects GeneMedi's different modalities and formats products for NFKBIA in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the NFKBIA target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]

Target IDGM-T51672
Target NameNFKBIA
Gene ID4792,18035,25493,695335,480291,101090622,282291,100058000
Gene Symbol and SynonymsEDAID2,IKBA,MAD-3,NFKBI,NFKBIA,RL/IF-1
Uniprot AccessionP25963,Q63746
Uniprot Entry NameIKBA_HUMAN,IKBA_RAT
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseN/A
Gene EnsemblENSG00000100906
Target ClassificationPathway


Pre-made anti-NFKBIA inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-NFKBIA monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-NFKBIA mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-NFKBIA monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species IKBA/ NFKBIA/ MAD-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NFKBIA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
NFKBIA proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made NFKBIA viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMAP000119Human NFKBIA Adenovirus plasmidBC002601HumanAdenovirus plasmidDetail
pGMLV000540human NFKBIA Lentivirus plasmidNM_020529HumanLentivirus plasmidDetail
vGMLV000540human NFKBIA Lentivirus particleNM_020529HumanLentivirus particleDetail
vGMAP000119Human NFKBIA Adenovirus particleBC002601HumanAdenovirus particleDetail
pGMAD000047rat Nfkbia Adenovirus plasmidNM_001105720.2RatAdenovirus plasmidDetail
pGMLPm003911mouse Nfkbia Lentivirus plasmidNM_010907MouseLentivirus plasmidDetail
vGMAD000047rat Nfkbia Adenovirus particleNM_001105720.2RatAdenovirus particleDetail
vGMLPm003911mouse Nfkbia Lentivirus particleNM_010907MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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