NFKBIA: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of NFKBIA. The page also collects GeneMedi's different modalities and formats products for NFKBIA in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the NFKBIA target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
Target ID | GM-T51672 |
Target Name | NFKBIA |
Gene ID | 4792,18035,25493,695335,480291,101090622,282291,100058000 |
Gene Symbol and Synonyms | EDAID2,IKBA,MAD-3,NFKBI,NFKBIA,RL/IF-1 |
Uniprot Accession | P25963,Q63746 |
Uniprot Entry Name | IKBA_HUMAN,IKBA_RAT |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000100906 |
Target Classification | Pathway |
Pre-made anti-NFKBIA inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-NFKBIA monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-NFKBIA mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-NFKBIA monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species IKBA/ NFKBIA/ MAD-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NFKBIA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
NFKBIA protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made NFKBIA viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMAP000119 | Human NFKBIA Adenovirus plasmid | BC002601 | Human | Adenovirus plasmid | Detail |
pGMLV000540 | human NFKBIA Lentivirus plasmid | NM_020529 | Human | Lentivirus plasmid | Detail |
vGMLV000540 | human NFKBIA Lentivirus particle | NM_020529 | Human | Lentivirus particle | Detail |
vGMAP000119 | Human NFKBIA Adenovirus particle | BC002601 | Human | Adenovirus particle | Detail |
pGMAD000047 | rat Nfkbia Adenovirus plasmid | NM_001105720.2 | Rat | Adenovirus plasmid | Detail |
pGMLPm003911 | mouse Nfkbia Lentivirus plasmid | NM_010907 | Mouse | Lentivirus plasmid | Detail |
vGMAD000047 | rat Nfkbia Adenovirus particle | NM_001105720.2 | Rat | Adenovirus particle | Detail |
vGMLPm003911 | mouse Nfkbia Lentivirus particle | NM_010907 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.