PDCD1,PD-1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of PD-1,PDCD1. The page also collects GeneMedi's different modalities and formats products for PD-1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PD-1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]

Pre-made PD-1-specific INN-index biosimilar (antibody&conjugates)-Pembrolizumab, Cetrelimab, Cadonilimab, Lorigerlimab, zimbirelimab, Tislelizumab, Nivolumab, Pucotenlimab, Balstilimab, Rulonilimab, Zimberelimab, Geptanolimab, Camrelizumab, Pimivalimab, Zeluvalimab, Sasanlimab, Spartalizumab, Prolgolimab, Vudalimab, Sintilimab, Toripalimab, Penpulimab, Fidasimtamab, Iparomlimab, Dostarlimab, Cemiplimab, Pidilizumab, Izuralimab, Retifanlimab, Tebotelimab, Lambrolizumab, Serplulimab, Budigalimab, Nofazinlimab, Finotonlimab, Ezabenlimab

Anti-PD-1 therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).

Cat No.	Products Name (INN Index)	INN Name	Previous Name	Target	Format	Order
GMP-Bios-ab-435	Pre-Made Pembrolizumab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Pembrolizumab	Lambrolizumab	PDCD1/PD-1	Whole mAb
GMP-Bios-ab-101	Pre-Made Cetrelimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Cetrelimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-088	Pre-Made Cadonilimab biosimilar, Bispecific Mixed mAb and scFv, Anti-PDCD1/PD-1;CTLA4/CTLA-4 antibody: Anti-CD279/PD1/SLEB2/hPD-1/hPD-l/hSLE1;CD/GSE/GRD4/ALPS5/CD152/IDDM12/CELIAC3 therapeutic antibody	Cadonilimab		PDCD1/PD-1; CTLA4/CTLA-4	Bispecific Mixed mAb and scFv
GMP-Bios-ab-679	Pre-Made Lorigerlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1;CTLA4/CTLA-4 Antibody: Anti-CD279/PD1/SLEB2/hPD-1/hPD-l/hSLE1;CD/GSE/GRD4/ALPS5/CD152/IDDM12/CELIAC3 therapeutic antibody	Lorigerlimab		PDCD1/PD-1;CTLA4/CTLA-4	Bispecific Mixed scFv (scFv-CH2-CH3-scFv)
GMP-Bios-INN-1058	Pre-Made Zimbirelimab Biosimilar, Whole Mab, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	zimbirelimab		PDCD1/PD-1	Whole  mAb
GMP-Bios-ab-581	Pre-Made Tislelizumab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Tislelizumab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-381	Pre-Made Nivolumab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Nivolumab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-459	Pre-Made Pucotenlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Pucotenlimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-044	Pre-Made Balstilimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Balstilimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-692	Pre-Made Rulonilimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Rulonilimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-648	Pre-Made Zimberelimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Zimberelimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-240	Pre-Made Geptanolimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Geptanolimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-090	Pre-Made Camrelizumab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Camrelizumab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-442	Pre-Made Pimivalimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Pimivalimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-644	Pre-Made Zeluvalimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Zeluvalimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-508	Pre-Made Sasanlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Sasanlimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-531	Pre-Made Spartalizumab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Spartalizumab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-458	Pre-Made Prolgolimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Prolgolimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-631	Pre-Made Vudalimab biosimilar, Bispecific Mixed mAb and scFv, Anti-CTLA4/CTLA-4;PDCD1/PD-1 Antibody: Anti-CD/GSE/GRD4/ALPS5/CD152/IDDM12/CELIAC3;CD279/SLEB2/hPD-1/hPD-l/hSLE1 therapeutic antibody	Vudalimab		CTLA4/CTLA-4;PDCD1/PD-1	Bispecific Mixed mAb and scFv
GMP-Bios-ab-523	Pre-Made Sintilimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Sintilimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-587	Pre-Made Toripalimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Toripalimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-436	Pre-Made Penpulimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Penpulimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-667	Pre-Made Fidasimtamab biosimilar, Whole mAb, Anti-PDCD1/PD-1;ERBB2/HER2 Antibody: Anti-CD279/PD1/SLEB2/hSLE1;CD340/neu/MLN 19/NEU/NGL/TKR1/VSCN2 therapeutic antibody	Fidasimtamab		PDCD1/PD-1;ERBB2/HER2	Bispecific Whole mAb
GMP-Bios-ab-672	Pre-Made Iparomlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Iparomlimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-154	Pre-Made Dostarlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Dostarlimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-097	Pre-Made Cemiplimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Cemiplimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-441	Pre-Made Pidilizumab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Pidilizumab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-287	Pre-Made Izuralimab biosimilar, Bispecific Mixed mAb and scFv, Anti-ICOS;PDCD1/PD-1 antibody: Anti-AILIM/CD278/CVID1;CD279/SLEB2/hPD-1/hPD-l/hSLE1 therapeutic antibody	Izuralimab		ICOS;PDCD1/PD-1	Bispecific Mixed mAb and scFv
GMP-Bios-ab-480	Pre-Made Retifanlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Retifanlimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-556	Pre-Made Tebotelimab biosimilar, Bispecific scFv with Crossover, Anti-PDCD1/PD-1;LAG3 Antibody: Anti-CD279/PD1/SLEB2/hPD-1/hPD-l/hSLE1;CD223 therapeutic antibody	Tebotelimab		PDCD1/PD-1;LAG3	Bispecific scFv with Crossover
GMP-Bios-ab-292	Pre-Made Lambrolizumab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Lambrolizumab	pembrolizumab	PDCD1/PD-1	Whole mAb
GMP-Bios-ab-515	Pre-Made Serplulimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Serplulimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-085	Pre-Made Budigalimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Budigalimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-684	Pre-Made Nofazinlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Nofazinlimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-215	Pre-Made Finotonlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Finotonlimab		PDCD1/PD-1	Whole mAb
GMP-Bios-ab-203	Pre-Made Ezabenlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1 Antibody: Anti-CD279/PD1/SLEB2/hSLE1 therapeutic antibody	Ezabenlimab		PDCD1/PD-1	Whole mAb

Pre-made anti-PD-1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-PD-1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PD-1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Cat No.	Antibody Name	Format	Classified by tag	Order
GM-Tg-hg-T59631-Ab	Anti-PD-1/PDCD1 monoclonal antibody	mab	Biofunctional antibody, Therapeutics Target antibody