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Pre-made Lorigerlimab benchmark antibody ( Whole mAb, anti-PDCD1/PD-1;CTLA4/CTLA-4 therapeutic antibody, Anti-CD279,PD1/SLEB2/hPD-1/hPD-l/hSLE1;CD/GSE/GRD4/ALPS5/CD152/IDDM12/CELIAC3 Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-679
Pre-Made Lorigerlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1;CTLA4/CTLA-4 Antibody: Anti-CD279/PD1/SLEB2/hPD-1/hPD-l/hSLE1;CD/GSE/GRD4/ALPS5/CD152/IDDM12/CELIAC3 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Order information
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry
| Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| GMP-Bios-ab-679-1mg | 1mg | Inquiry | ||
| GMP-Bios-ab-679-10mg | 10mg | Inquiry | ||
| GMP-Bios-ab-679-100mg | 100mg | Inquiry | ||
| GMP-Bios-ab-679-xmg | ＞100mg | Inquiry | ||
| Shipping Cost: | 760.00 | |||
| Total: | ||||
Description
| Products Name (INN Index) | Pre-Made Lorigerlimab biosimilar, Whole mAb, Anti-PDCD1/PD-1;CTLA4/CTLA-4 Antibody: Anti-CD279/PD1/SLEB2/hPD-1/hPD-l/hSLE1;CD/GSE/GRD4/ALPS5/CD152/IDDM12/CELIAC3 therapeutic antibody |
| INN Name | Lorigerlimab |
| Target | PD-1;CTLA-4 |
| Format | Bispecific Mixed scFv (scFv-CH2-CH3-scFv) |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | IgG4;IgG4 |
| VD LC | Kappa;Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Active |
| 100% SI Structure | None;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;5xj3:AB/5tru:HL/6jc2:HL/6rp8:hl/7erx:HL |
| Year Proposed | 2021 |
| Year Recommended | na |
| Companies | MacroGenics |
| Conditions Approved | na |
| Conditions Active | Solid tumours |
| Conditions Discontinued | na |
| Development Tech | Dual-Affinity Re-Targeting Technology |
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