CSF3R,G-CSF-R: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of G-CSF-R,CSF3R. The page also collects GeneMedi's different modalities and formats products for G-CSF-R in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the G-CSF-R target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]
Target ID | GM-T98913 |
Target Name | G-CSF-R |
Gene ID | 1441 |
Gene Official Name | CSF3R |
Gene Alias | CD114, GCSFR, SCN7 |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, INN Index, Immuno-oncology Target |
Pre-made G-CSF-R-specific INN-index biosimilar (antibody&conjugates)-eflapegrastim, efbemalenograstim alfa, filgrastim, balugrastim, Anumigilimab, pegfilgrastim
Anti-G-CSF-R therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Pre-made anti-G-CSF-R inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-G-CSF-R benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-G-CSF-R mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Cat No. | Antibody Name | Format | Classified by tag | Order |
GM-Tg-hg-T98913-Ab | Anti-G-CSF-R/CSF3R monoclonal antibody | mab | Biofunctional antibody, Therapeutics Target antibody | ![]() |