Human TIMP3/HSMRK222/ K222 ORF/cDNA clone-Lentivirus plasmid (NM_000362)
Pre-made Human TIMP3/HSMRK222/ K222 Lentiviral expression plasmid for TIMP3 lentivirus packaging, TIMP3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMLP000407 | Human TIMP3 Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMLP000407 |
Gene Name | TIMP3 |
Accession Number | NM_000362 |
Gene ID | 7078 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 636 bp |
Gene Alias | HSMRK222, K222, K222TA2, SFD |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Sequence | ATGACCCCTTGGCTCGGGCTCATCGTGCTCCTGGGCAGCTGGAGCCTGGGGGACTGGGGCGCCGAGGCGTGCACATGCTCGCCCAGCCACCCCCAGGACGCCTTCTGCAACTCCGACATCGTGATCCGGGCCAAGGTGGTGGGGAAGAAGCTGGTAAAGGAGGGGCCCTTCGGCACGCTGGTCTACACCATCAAGCAGATGAAGATGTACCGAGGCTTCACCAAGATGCCCCATGTGCAGTACATCCATACGGAAGCTTCCGAGAGTCTCTGTGGCCTTAAGCTGGAGGTCAACAAGTACCAGTACCTGCTGACAGGTCGCGTCTATGATGGCAAGATGTACACGGGGCTGTGCAACTTCGTGGAGAGGTGGGACCAGCTCACCCTCTCCCAGCGCAAGGGGCTGAACTATCGGTATCACCTGGGTTGTAACTGCAAGATCAAGTCCTGCTACTACCTGCCTTGCTTTGTGACTTCCAAGAACGAGTGTCTCTGGACCGACATGCTCTCCAATTTCGGTTACCCTGGCTACCAGTCCAAACACTACGCCTGCATCCGGCAGAAGGGCGGCTACTGCAGCTGGTACCGAGGATGGGCCCCCCCGGATAAAAGCATCATCAATGCCACAGACCCCTGA |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-SE1339-Ab | Anti-TIMP3/ HSMRK222/ K222 functional antibody |
Target Antigen | GM-Tg-g-SE1339-Ag | TIMP3 protein |
ORF Viral Vector | pGMPC000772 | Human TIMP3 Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | pGMLP000407 | Human TIMP3 Lentivirus plasmid |
ORF Viral Vector | pGMAP000031 | Human TIMP3 Adenovirus plasmid |
ORF Viral Vector | vGMLP000407 | Human TIMP3 Lentivirus particle |
ORF Viral Vector | vGMAP000031 | Human TIMP3 Adenovirus particle |
Target information
Target ID | GM-SE1339 |
Target Name | TIMP3 |
Gene ID | 7078, 21859, 574381, 25358, 101091215, 481289, 282094, 100033947 |
Gene Symbol and Synonyms | HSMRK222,K222,K222TA2,SFD,Timp-3,TIMP3 |
Uniprot Accession | P35625 |
Uniprot Entry Name | TIMP3_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Not Available |
Disease | Juvenile astrocytoma |
Gene Ensembl | ENSG00000100234 |
Target Classification | Not Available |
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]
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