Human PMP22/CIDP/CMT1A ORF/cDNA clone-Lentivirus plasmid (NM_000304)

Cat. No.: pGMLP000512
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PMP22/CIDP/CMT1A Lentiviral expression plasmid for PMP22 lentivirus packaging, PMP22 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000512
Gene Name PMP22
Accession Number NM_000304
Gene ID 5376
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 483 bp
Gene Alias CIDP,CMT1A,CMT1E,DSS,GAS-3,GAS3,HMSNIA,HNPP,Sp110
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCTCCTCCTGTTGCTGAGTATCATCGTCCTCCACGTCGCGGTGCTGGTGCTGCTGTTCGTCTCCACGATCGTCAGCCAATGGATCGTGGGCAATGGACACGCAACTGATCTCTGGCAGAACTGTAGCACCTCTTCCTCAGGAAATGTCCACCACTGTTTCTCATCATCACCAAACGAATGGCTGCAGTCTGTCCAGGCCACCATGATCCTGTCGATCATCTTCAGCATTCTGTCTCTGTTCCTGTTCTTCTGCCAACTCTTCACCCTCACCAAGGGGGGCAGGTTTTACATCACTGGAATCTTCCAAATTCTTGCTGGTCTGTGCGTGATGAGTGCTGCGGCCATCTACACGGTGAGGCACCCGGAGTGGCATCTCAACTCGGATTACTCCTACGGTTTCGCCTACATCCTGGCCTGGGTGGCCTTCCCCCTGGCCCTTCTCAGCGGTGTCATCTATGTGATCTTGCGGAAACGCGAATGA
ORF Protein Sequence MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP1395-Ab Anti-PMP22/ CIDP/ CMT1A monoclonal antibody
    Target Antigen GM-Tg-g-MP1395-Ag PMP22 VLP (virus-like particle)
    ORF Viral Vector pGMLP000512 Human PMP22 Lentivirus plasmid
    ORF Viral Vector pGMAP000148 Human PMP22 Adenovirus plasmid
    ORF Viral Vector vGMLP000512 Human PMP22 Lentivirus particle
    ORF Viral Vector vGMAP000148 Human PMP22 Adenovirus particle


    Target information

    Target ID GM-MP1395
    Target Name PMP22
    Gene ID 5376, 18858, 693527, 24660, 101092215, 479509, 534497, 100034146
    Gene Symbol and Synonyms CIDP,CMT1A,CMT1E,DSS,GAS-3,GAS3,HMSNIA,HNPP,PMP-22,PMP22,Sp110,Tr,TRE002,trembler
    Uniprot Accession Q01453
    Uniprot Entry Name PMP22_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000109099
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]



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