Human APP/AAA/ ABETA ORF/cDNA clone-Adenovirus particle (NM_201414.2)

Pre-made Human APP/AAA/ ABETA Adenovirus for APP overexpression in-vitro and in-vivo. The APP adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified APP-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

Target products collectionGo to APP/AAA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD000012 Human APP Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD000012
Gene Name APP
Accession Number NM_201414.2
Gene ID 351
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 2088 bp
Gene Alias AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, preA4
Fluorescent Reporter EGFP
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-011 Pre-Made Aducanumab biosimilar, Whole mAb, Anti-APP Antibody: Anti-AAA/AD1/PN2/ABPP/CVAP/ABETA/PN-II/preA4/CTFgamma therapeutic antibody
    Biosimilar GMP-Bios-ab-527 Pre-Made Solanezumab biosimilar, Whole mAb, Anti-APP Antibody: Anti-AAA/AD1/PN2/ABPP/CVAP/ABETA/PN-II/preA4/CTFgamma therapeutic antibody
    Biosimilar GMP-Bios-ab-232 Pre-Made Gantenerumab biosimilar, Whole mAb, Anti-APP Antibody: Anti-AAA/AD1/PN2/ABPP/CVAP/ABETA/PN-II/preA4/CTFgamma therapeutic antibody
    Biosimilar GMP-Bios-ab-046 Pre-Made Bapineuzumab biosimilar, Whole mAb, Anti-APP Antibody: Anti-AAA/AD1/PN2/ABPP/CVAP/ABETA/PN-II/preA4/CTFgamma therapeutic antibody
    Biosimilar GMP-Bios-ab-450 Pre-Made Ponezumab biosimilar, Whole mAb, Anti-APP Antibody: Anti-AAA/AD1/PN2/ABPP/CVAP/ABETA/PN-II/preA4/CTFgamma therapeutic antibody
    Biosimilar GMP-Bios-ab-153 Pre-Made Donanemab biosimilar, Whole mAb, Anti-APP Antibody: Anti-AAA/AD1/PN2/ABPP/CVAP/ABETA/PN-II/preA4/CTFgamma therapeutic antibody
    Biosimilar GMP-Bios-ab-300 Pre-Made Lecanemab biosimilar, Whole mAb, Anti-APP Antibody: Anti-AAA/AD1/PN2/ABPP/CVAP/ABETA/PN-II/preA4/CTFgamma therapeutic antibody
    Biosimilar GMP-Bios-ab-122 Pre-Made Crenezumab biosimilar, Whole mAb, Anti-APP Antibody: Anti-AAA/AD1/PN2/ABPP/CVAP/ABETA/PN-II/preA4/CTFgamma therapeutic antibody
    Target Antibody GM-Tg-g-T87024-Ab Anti-A4/ APP/ AAA monoclonal antibody
    Target Antigen GM-Tg-g-T87024-Ag APP VLP (virus-like particle)
    ORF Viral Vector pGMLV000006 Human APP Lentivirus plasmid
    ORF Viral Vector pGMLV000448 Human APP Lentivirus plasmid
    ORF Viral Vector pGMLV000767 Human APP Lentivirus plasmid
    ORF Viral Vector pGMLV001205 Human APP Lentivirus plasmid
    ORF Viral Vector pGMLV001236 Human APP Lentivirus plasmid
    ORF Viral Vector pGMAD000012 Human APP Adenovirus plasmid
    ORF Viral Vector pGMAD000406 Human APP Adenovirus plasmid
    ORF Viral Vector pGMAD000683 Human APP Adenovirus plasmid
    ORF Viral Vector pGMAD000999 Rat App Adenovirus plasmid
    ORF Viral Vector pGMAD001157 Rat App Adenovirus plasmid
    ORF Viral Vector pGMAP000180 Human APP Adenovirus plasmid
    ORF Viral Vector vGMLV000006 Human APP Lentivirus particle
    ORF Viral Vector vGMLV000448 Human APP Lentivirus particle
    ORF Viral Vector vGMLV000767 Human APP Lentivirus particle
    ORF Viral Vector vGMLV001205 Human APP Lentivirus particle
    ORF Viral Vector vGMLV001236 Human APP Lentivirus particle
    ORF Viral Vector vGMAD000012 Human APP Adenovirus particle
    ORF Viral Vector vGMAD000406 Human APP Adenovirus particle
    ORF Viral Vector vGMAD000683 Human APP Adenovirus particle
    ORF Viral Vector vGMAD000999 Rat App Adenovirus particle
    ORF Viral Vector vGMAD001157 Rat App Adenovirus particle
    ORF Viral Vector vGMAP000180 Human APP Adenovirus particle
    ORF Viral Vector pGMLV002219 Mouse App Lentivirus plasmid


    Target information

    Target ID GM-T87024
    Target Name APP
    Gene ID 351, 11820, 100427716, 54226, 101085564, 403407, 280722, 100066294
    Gene Symbol and Synonyms AAA,ABETA,ABPP,AD1,Adap,Ag,alpha-sAPP,APP,APPI,betaApp,CTFgamma,CVAP,E030013M08Rik,PN-II,PN2,preA4
    Uniprot Accession P05067
    Uniprot Entry Name A4_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, INN Index
    Disease Not Available
    Gene Ensembl ENSG00000142192
    Target Classification Not Available

    This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.