Canine β-CTx antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-CAN-B-CTx-Ag01	Recombinant Canine β-CTx protein	3090
GMP-CAN-B-CTx-Ab01	Anti-Canine β-CTx mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-B-CTx-Ab02	Anti-Canine β-CTx mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-B-CTx-Ab03	Anti-Canine β-CTx mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-B-CTx-Ab04	Anti-Canine β-CTx mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-CAN-B-CTx-Ag01
Product Name	Recombinant Canine β-CTx protein
Target/Biomarker	Canine β-isomerized C-terminal telopeptides (β-CTx)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine β-isomerized C-terminal telopeptides antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in β-CTx level test of animal Dog/Canine with osteoporosis.
Tag	His
Products description	Recombinant Canine β-CTx protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-B-CTx-Ab01, GMP-CAN-B-CTx-Ab02, GMP-CAN-B-CTx-Ab03, GMP-CAN-B-CTx-Ab04
Product Name	Anti-Canine β-CTx mouse monoclonal antibody (mAb)
Target/Biomarker	Canine β-isomerized C-terminal telopeptides (β-CTx)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Canine β-isomerized C-terminal telopeptides antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in β-CTx level test of animal Dog/Canine with osteoporosis.
Tag	mFc
Products description	Anti-Canine β-CTx mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Canine β-CTx (Beta-CrossLaps) is a pivotal biomarker, deeply interwoven with the intricacies of canine bone health. It takes its place within the canine species, Canis lupus familiaris, as an essential fragment of type I collagen, a major component of bone tissue. Its significance is underscored by its role as a marker of bone resorption, offering insights into the dynamic process of bone turnover in dogs. In the realm of bone metabolism, β-CTx stands as a sentinel of bone resorption, the process through which old or damaged bone tissue is broken down. This phenomenon is orchestrated by specialized cells called osteoclasts, responsible for initiating the release of fragments of type I collagen, including β-CTx, into the bloodstream. The measurement of Canine β-CTx provides a quantitative assessment of the rate of bone resorption in dogs. Elevated levels of β-CTx indicate heightened bone turnover, suggesting an imbalance in bone metabolism. This imbalance can be a harbinger of bone disorders or diseases, including osteoporosis, where bone resorption outpaces bone formation. It is also relevant in conditions like bone fractures or periodontal disease, where bone tissue is being actively remodeled.

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