Canine Calmodulin antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-CAN-Calmodulin-Ag01	Recombinant Canine Calmodulin protein	3090
GMP-CAN-Calmodulin-Ab01	Anti-Canine Calmodulin mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-Calmodulin-Ab02	Anti-Canine Calmodulin mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-Calmodulin-Ab03	Anti-Canine Calmodulin mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-Calmodulin-Ab04	Anti-Canine Calmodulin mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-CAN-Calmodulin-Ag01
Product Name	Recombinant Canine Calmodulin protein
Target/Biomarker	Canine Calmodulin
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Calmodulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Dog/Canine with Hormone disorders.
Tag	His
Products description	Recombinant Canine Calmodulin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-Calmodulin-Ab01, GMP-CAN-Calmodulin-Ab02, GMP-CAN-Calmodulin-Ab03, GMP-CAN-Calmodulin-Ab04
Product Name	Anti-Canine Calmodulin mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Calmodulin
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Canine Calmodulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Dog/Canine with Hormone disorders.
Tag	mFc
Products description	Anti-Canine Calmodulin mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Calmodulin is a highly conserved, multifunctional intracellular calcium-binding protein found across a wide range of eukaryotic species, including cats (felines). It plays a pivotal role in transducing calcium signals by binding calcium ions and then modifying its interactions with various target proteins. This process is crucial for the regulation of numerous cellular functions such as muscle contraction, intracellular movement, cell division, and signal transduction pathways. Function and Importance in Felines: In cats, as in other organisms, calmodulin functions as a key mediator in calcium signaling pathways that affect many aspects of cellular physiology: Muscle Contraction: Calmodulin activates myosin light-chain kinase, which is essential for smooth muscle contraction. This mechanism is vital for various physiological processes including cardiovascular function and gastrointestinal motility. Neurotransmitter Release: It plays a role in the release of neurotransmitters at synapses, influencing nerve impulse transmission and contributing to brain and nervous system function. Cell Cycle Regulation: Calmodulin is involved in the regulation of the cell cycle and cell proliferation. It activates various enzymes and proteins critical for cell growth and division. Signal Transduction: It participates in several signal transduction pathways, impacting cellular responses to hormonal and environmental stimuli. Research and Clinical Implications: Disease Research: Understanding the role of calmodulin in cats can contribute to research into diseases that involve calcium signaling abnormalities, such as hypertrophic cardiomyopathy, a common heart disease in cats. Abnormalities in calcium signaling and calmodulin function could potentially contribute to the pathogenesis of such conditions. Drug Targets: Calmodulin and the pathways it regulates may serve as potential targets for therapeutic interventions. Drugs that modulate calmodulin activity could influence processes like muscle contraction and cell proliferation, offering avenues for treating diseases with underlying calcium signaling disruptions. Diagnostic and Therapeutic Applications: While specific diagnostic tests targeting calmodulin in cats are not commonly described, the understanding of calmodulin's role in feline physiology underpins various aspects of veterinary medicine, from the diagnosis to the treatment of diseases. In summary, calmodulin in cats is a critical protein that mediates numerous calcium-dependent processes essential for healthy cellular function. Its wide-ranging impact on cellular physiology underscores the importance of calcium signaling in feline health and disease. Further research into calmodulin's specific roles and mechanisms in cats could enhance understanding and treatment of diseases related to calcium signaling dysregulation.

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