FKBP1A: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of FKBP1A. The page also collects GeneMedi's different modalities and formats products for FKBP1A in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the FKBP1A target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008]
|Gene Symbol and Synonyms||Fkbp,FKBP-12,FKBP-1A,FKBP1,FKBP12,FKBP1A,FKBP1B,Fkbp2,PKC12,PKCI2,PPIASE|
|Uniprot Entry Name||FKB1A_HUMAN,FKB1A_RAT,FKB1A_BOVIN|
|Protein Sub-location||Introcelluar Protein|
Pre-made anti-FKBP1A inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-FKBP1A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-FKBP1A mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
|Antibody Name||Species||Format||Classified by tag||Detail|
|Anti-FKBP1A monoclonal antibody||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||mab||Therapeutics Target antibody||Detail|
Recombinant multi-species FKB1A/ FKBP1A/ FKBP-12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FKBP1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
|Products Name||Species||Expression Platform||Detail|
|FKBP1A protein||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||Mammalian cell||Detail|
Pre-made FKBP1A viral vector in GM Promise-ORFTM
|Cat No.||Products name||NM ID||Species||Type||Detail|
|pGMLP000449||human FKBP1A Lentivirus plasmid||NM_000801||Human||Lentivirus plasmid||Detail|
|vGMLP000449||human FKBP1A Lentivirus particle||NM_000801||Human||Lentivirus particle||Detail|
|vGMAP000487||Human FKBP1A Adenovirus particle||BC119732||Human||Adenovirus particle||Detail|
|vGMAP000355||Human FKBP1A Adenovirus particle||BC119732||Human||Adenovirus particle||Detail|
|pGMAP000355||Human FKBP1A Adenovirus plasmid||BC119732||Human||Adenovirus plasmid||Detail|
|pGMAP000487||Human FKBP1A Adenovirus plasmid||BC119732||Human||Adenovirus plasmid||Detail|
|pGMLPm000087||mouse Fkbp1a Lentivirus plasmid||NM_001302077||Mouse||Lentivirus plasmid||Detail|
|vGMLPm000087||mouse Fkbp1a Lentivirus particle||NM_001302077||Mouse||Lentivirus particle||Detail|
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.