GCGR: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of GCGR. The page also collects GeneMedi's different modalities and formats products for GCGR in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GCGR target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]

Target IDGM-T60182
Target NameGCGR
Gene ID2642,14527,24953,714542,483368,101099672,515433,100055316
Gene Symbol and SynonymsGCGR,GGR,GL-R,GR,MVAH
Uniprot AccessionP47871,P30082
Uniprot Entry NameGLR_HUMAN,GLR_RAT
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target, INN Index
DiseaseN/A
Gene EnsemblENSG00000215644
Target ClassificationGPCR


Pre-made GCGR-specific INN-index biosimilar (antibody&conjugates)

Anti-GCGR therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).

Cat No.Products Name (INN Index)INN Name Previous Name Target FormatDetail
GMP-Bios-ab-124Pre-Made Crotedumab biosimilar, Whole mAb, Anti-GCGR Antibody: Anti-GGR/GL-R/MVAH therapeutic antibodyCrotedumabGCGRWhole mAbDetail
GMP-Bios-INN-857Pre-Made Glucagon Biosimilar, Recombinant Protein targeting GCGR: Recombinant therapeutic protein targeting GGR/GL-R/MVAHglucagonGCGRRecombinant ProteinDetail

Click to check more INN-indexed antibody & protein biosimilar



Pre-made anti-GCGR inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-GCGR benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GCGR mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-GCGR monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Multi-species GLR/ GCGR/ GGR VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GCGR VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
GCGR VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made GCGR viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLP003748human GCGR Lentivirus plasmidNM_000160HumanLentivirus plasmidDetail
vGMLP003748human GCGR Lentivirus particleNM_000160HumanLentivirus particleDetail
pGMLPm005312mouse Gcgr Lentivirus plasmidNM_008101.2MouseLentivirus plasmidDetail
vGMLPm005312mouse Gcgr Lentivirus particleNM_008101.2MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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