Human MAPK14/CSBP/ CSBP1 ORF/cDNA clone-Adenovirus plasmid (NM_001315.2)

Pre-made Human MAPK14/CSBP/ CSBP1 adenoviral expression plasmid for MAPK14 adenovirus packaging, MAPK14 adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

Target products collectionGo to p38 alpha/MAPK14/CSBP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMAD000565 Human MAPK14 Adenovirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMAD000565
Gene Name MAPK14
Accession Number NM_001315.2
Gene ID 1432
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 1083 bp
Gene Alias CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, p38, p38ALPHA, PRKM14, PRKM15, RK, SAPK2A
Fluorescent Reporter EGFP
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
Sequence ATGTCTCAGGAGAGGCCCACGTTCTACCGGCAGGAGCTGAACAAGACAATCTGGGAGGTGCCCGAGCGTTACCAGAACCTGTCTCCAGTGGGCTCTGGCGCCTATGGCTCTGTGTGTGCTGCTTTTGACACAAAAACGGGGTTACGTGTGGCAGTGAAGAAGCTCTCCAGACCATTTCAGTCCATCATTCATGCGAAAAGAACCTACAGAGAACTGCGGTTACTTAAACATATGAAACATGAAAATGTGATTGGTCTGTTGGACGTTTTTACACCTGCAAGGTCTCTGGAGGAATTCAATGATGTGTATCTGGTGACCCATCTCATGGGGGCAGATCTGAACAACATTGTGAAATGTCAGAAGCTTACAGATGACCATGTTCAGTTCCTTATCTACCAAATTCTCCGAGGTCTAAAGTATATACATTCAGCTGACATAATTCACAGGGACCTAAAACCTAGTAATCTAGCTGTGAATGAAGACTGTGAGCTGAAGATTCTGGATTTTGGACTGGCTCGGCACACAGATGATGAAATGACAGGCTACGTGGCCACTAGGTGGTACAGGGCTCCTGAGATCATGCTGAACTGGATGCATTACAACCAGACAGTTGATATTTGGTCAGTGGGATGCATAATGGCCGAGCTGTTGACTGGAAGAACATTGTTTCCTGGTACAGACCATATTAACCAGCTTCAGCAGATTATGCGTCTGACAGGAACACCCCCCGCTTATCTCATTAACAGGATGCCAAGCCATGAGGCAAGAAACTATATTCAGTCTTTGACTCAGATGCCGAAGATGAACTTTGCGAATGTATTTATTGGTGCCAATCCCCTGGCTGTCGACTTGCTGGAGAAGATGCTTGTATTGGACTCAGATAAGAGAATTACAGCGGCCCAAGCCCTTGCACATGCCTACTTTGCTCAGTACCACGATCCTGATGATGAACCAGTGGCCGATCCTTATGATCAGTCCTTTGAAAGCAGGGACCTCCTTATAGATGAGTGGAAAAGCCTGACCTATGATGAAGTCATCAGCTTTGTGCCACCACCCCTTGACCAAGAAGAGATGGAGTCCTGA

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T65864-Ab Anti-p38 alpha monoclonal antibody
    Target Antigen GM-Tg-g-T65864-Ag p38 alpha/MAPK14 protein
    ORF Viral Vector pGMAD000565 Human MAPK14 Adenovirus plasmid
    ORF Viral Vector pGMPC000541 Human MAPK14 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMAP000408 Human MAPK14 Adenovirus plasmid
    ORF Viral Vector pGMLP-SPh-057 Human MAPK14 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-131 Human MAPK14 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-197 Human MAPK14 Adenovirus plasmid
    ORF Viral Vector pGMAP-SPh-271 Human MAPK14 Adenovirus plasmid
    ORF Viral Vector vGMAD000565 Human MAPK14 Adenovirus particle
    ORF Viral Vector vGMAP000408 Human MAPK14 Adenovirus particle
    ORF Viral Vector vGMLP-SPh-057 Human MAPK14 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-131 Human MAPK14 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-197 Human MAPK14 Adenovirus particle
    ORF Viral Vector vGMAP-SPh-271 Human MAPK14 Adenovirus particle


    Target information

    Target ID GM-T65864
    Target Name p38 alpha
    Gene ID 1432, 26416, 718976, 81649, 101101135, 403856, 534492, 100063532
    Gene Symbol and Synonyms Crk1,CSBP,CSBP1,CSBP2,CSPB1,EXIP,Hog,MAPK14,Mxi2,p38,p38-alpha,p38a,p38ALPHA,p38Hog,p38MAPK,PRKM14,PRKM15,RK,SAPK2A
    Uniprot Accession Q16539
    Uniprot Entry Name MK14_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease Breast Cancer
    Gene Ensembl ENSG00000112062
    Target Classification Checkpoint-Immuno Oncology, Kinase

    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]



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