Recombinant multi-species HAVR2/ TIM-3/ HAVCR2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIM-3/HAVCR2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TIM-3, gene name: HAVCR2, also named as CD366, HAVcr-2, KIM-3, TIM3, TIMD-3, TIMD3, Tim-3. The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-IO140-Ag-1	Human TIM-3/HAVCR2 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-IO140-Ag-1	Rat TIM-3/HAVCR2 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-IO140-Ag-1	Mouse TIM-3/HAVCR2 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-IO140-Ag-1	Cynomolgus/ Rhesus macaque TIM-3/HAVCR2 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-IO140-Ag-1	Feline TIM-3/HAVCR2 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-IO140-Ag-1	Canine TIM-3/HAVCR2 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IO140-Ag-1	Bovine TIM-3/HAVCR2 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IO140-Ag-1	Equine TIM-3/HAVCR2 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-IO140-Ag, GM-Tg-rg-IO140-Ag, GM-Tg-mg-IO140-Ag, GM-Tg-cynog-IO140-Ag, GM-Tg-felg-IO140-Ag, GM-Tg-cang-IO140-Ag, GM-Tg-bovg-IO140-Ag, GM-Tg-equg-IO140-Ag-1
Products Name	TIM-3/HAVCR2 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	TIM-3
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIM-3/HAVCR2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.