Recombinant multi-species PAK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to PAK4/PAK4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PAK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PAK4, gene name: PAK4, also named as . PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0054-Ag-1Human PAK4 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0054-Ag-1Rat PAK4 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0054-Ag-1Mouse PAK4 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0054-Ag-1Cynomolgus/ Rhesus macaque PAK4 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0054-Ag-1Feline PAK4 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0054-Ag-1Canine PAK4 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0054-Ag-1Bovine PAK4 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0054-Ag-1Equine PAK4 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-IP0054-Ag, GM-Tg-rg-IP0054-Ag, GM-Tg-mg-IP0054-Ag, GM-Tg-cynog-IP0054-Ag,
GM-Tg-felg-IP0054-Ag, GM-Tg-cang-IP0054-Ag, GM-Tg-bovg-IP0054-Ag, GM-Tg-equg-IP0054-Ag-1
Products Name PAK4 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePAK4
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PAK4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.