Recombinant multi-species HIF1A/ HIF-1A/ HIF-1-alpha protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HIF-1A/HIF1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HIF-1A, gene name: HIF1A, also named as HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011].

Order information

* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry

Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-IP0067-Ag-1	Human HIF-1A/HIF1A protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-IP0067-Ag-1	Rat HIF-1A/HIF1A protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-IP0067-Ag-1	Mouse HIF-1A/HIF1A protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-IP0067-Ag-1	Cynomolgus/ Rhesus macaque HIF-1A/HIF1A protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-IP0067-Ag-1	Feline HIF-1A/HIF1A protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-IP0067-Ag-1	Canine HIF-1A/HIF1A protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP0067-Ag-1	Bovine HIF-1A/HIF1A protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP0067-Ag-1	Equine HIF-1A/HIF1A protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-IP0067-Ag, GM-Tg-rg-IP0067-Ag, GM-Tg-mg-IP0067-Ag, GM-Tg-cynog-IP0067-Ag, GM-Tg-felg-IP0067-Ag, GM-Tg-cang-IP0067-Ag, GM-Tg-bovg-IP0067-Ag, GM-Tg-equg-IP0067-Ag-1
Products Name	HIF-1A/HIF1A protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	HIF-1A
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HIF-1A/HIF1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.