Recombinant multi-species CD276/ 4Ig-B7-H3/ B7-H3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to CD276/CD276 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CD276 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CD276, gene name: CD276, also named as 4Ig-B7-H3, B7-H3, B7H3, B7RP-2. The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

Order information


* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry

Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0069-Ag-1Human CD276 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0069-Ag-1Rat CD276 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0069-Ag-1Mouse CD276 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0069-Ag-1Cynomolgus/ Rhesus macaque CD276 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0069-Ag-1Feline CD276 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0069-Ag-1Canine CD276 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0069-Ag-1Bovine CD276 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0069-Ag-1Equine CD276 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0069-Ag, GM-Tg-rg-IP0069-Ag, GM-Tg-mg-IP0069-Ag, GM-Tg-cynog-IP0069-Ag,
GM-Tg-felg-IP0069-Ag, GM-Tg-cang-IP0069-Ag, GM-Tg-bovg-IP0069-Ag, GM-Tg-equg-IP0069-Ag-1
Products Name CD276 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCD276
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CD276 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.