Recombinant multi-species MAPK5/ MAPKAPK5/ MAPKAP-K5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAPKAPK5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: MAPKAPK5, gene name: MAPKAPK5, also named as MAPKAP-K5, MK-5, MK5, PRAK. The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0100-Ag-1Human MAPKAPK5 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0100-Ag-1Rat MAPKAPK5 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0100-Ag-1Mouse MAPKAPK5 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0100-Ag-1Cynomolgus/ Rhesus macaque MAPKAPK5 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0100-Ag-1Feline MAPKAPK5 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0100-Ag-1Canine MAPKAPK5 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0100-Ag-1Bovine MAPKAPK5 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0100-Ag-1Equine MAPKAPK5 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0100-Ag, GM-Tg-rg-IP0100-Ag, GM-Tg-mg-IP0100-Ag, GM-Tg-cynog-IP0100-Ag,
GM-Tg-felg-IP0100-Ag, GM-Tg-cang-IP0100-Ag, GM-Tg-bovg-IP0100-Ag, GM-Tg-equg-IP0100-Ag-1
Products Name MAPKAPK5 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameMAPKAPK5
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAPKAPK5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.