Recombinant multi-species SF3B1/ Hsh155/ MDS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SF3B1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SF3B1, gene name: SF3B1, also named as Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155. This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0119-Ag-1Human SF3B1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0119-Ag-1Rat SF3B1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0119-Ag-1Mouse SF3B1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0119-Ag-1Cynomolgus/ Rhesus macaque SF3B1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0119-Ag-1Feline SF3B1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0119-Ag-1Canine SF3B1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0119-Ag-1Bovine SF3B1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0119-Ag-1Equine SF3B1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0119-Ag, GM-Tg-rg-IP0119-Ag, GM-Tg-mg-IP0119-Ag, GM-Tg-cynog-IP0119-Ag,
GM-Tg-felg-IP0119-Ag, GM-Tg-cang-IP0119-Ag, GM-Tg-bovg-IP0119-Ag, GM-Tg-equg-IP0119-Ag-1
Products Name SF3B1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameSF3B1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SF3B1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.