Recombinant multi-species DHC24/ DHCR24/ DCE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to DHCR24/DHCR24 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHCR24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: DHCR24, gene name: DHCR24, also named as DCE, Nbla03646, SELADIN1, seladin-1. This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008].

Order information


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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0124-Ag-1Human DHCR24 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0124-Ag-1Rat DHCR24 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0124-Ag-1Mouse DHCR24 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0124-Ag-1Cynomolgus/ Rhesus macaque DHCR24 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0124-Ag-1Feline DHCR24 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0124-Ag-1Canine DHCR24 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0124-Ag-1Bovine DHCR24 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0124-Ag-1Equine DHCR24 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0124-Ag, GM-Tg-rg-IP0124-Ag, GM-Tg-mg-IP0124-Ag, GM-Tg-cynog-IP0124-Ag,
GM-Tg-felg-IP0124-Ag, GM-Tg-cang-IP0124-Ag, GM-Tg-bovg-IP0124-Ag, GM-Tg-equg-IP0124-Ag-1
Products Name DHCR24 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameDHCR24
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHCR24 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.