Recombinant multi-species SOCS3/ ATOD4/ CIS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to SOCS3/SOCS3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOCS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SOCS3, gene name: SOCS3, also named as ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0224-Ag-1Human SOCS3 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0224-Ag-1Rat SOCS3 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0224-Ag-1Mouse SOCS3 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0224-Ag-1Cynomolgus/ Rhesus macaque SOCS3 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0224-Ag-1Feline SOCS3 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0224-Ag-1Canine SOCS3 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0224-Ag-1Bovine SOCS3 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0224-Ag-1Equine SOCS3 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0224-Ag, GM-Tg-rg-IP0224-Ag, GM-Tg-mg-IP0224-Ag, GM-Tg-cynog-IP0224-Ag,
GM-Tg-felg-IP0224-Ag, GM-Tg-cang-IP0224-Ag, GM-Tg-bovg-IP0224-Ag, GM-Tg-equg-IP0224-Ag-1
Products Name SOCS3 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameSOCS3
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOCS3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.