Recombinant multi-species CLCN4/ CLC4/ ClC-4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to CLCN4/CLCN4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLCN4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CLCN4, gene name: CLCN4, also named as CLC4, ClC-4, ClC-4A, MRX15, MRX49. The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0554-Ag-1Human CLCN4 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0554-Ag-1Rat CLCN4 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0554-Ag-1Mouse CLCN4 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0554-Ag-1Cynomolgus/ Rhesus macaque CLCN4 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0554-Ag-1Feline CLCN4 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0554-Ag-1Canine CLCN4 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0554-Ag-1Bovine CLCN4 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0554-Ag-1Equine CLCN4 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0554-Ag, GM-Tg-rg-IP0554-Ag, GM-Tg-mg-IP0554-Ag, GM-Tg-cynog-IP0554-Ag,
GM-Tg-felg-IP0554-Ag, GM-Tg-cang-IP0554-Ag, GM-Tg-bovg-IP0554-Ag, GM-Tg-equg-IP0554-Ag-1
Products Name CLCN4 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCLCN4
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLCN4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.