Recombinant multi-species CLN8/ C8orf61/ EPMR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to CLN8/CLN8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLN8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CLN8, gene name: CLN8, also named as C8orf61, EPMR. This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with a disorder characterized by progressive epilepsy with cognitive disabilities (EPMR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain. [provided by RefSeq, Jul 2017].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0563-Ag-1Human CLN8 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0563-Ag-1Rat CLN8 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0563-Ag-1Mouse CLN8 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0563-Ag-1Cynomolgus/ Rhesus macaque CLN8 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0563-Ag-1Feline CLN8 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0563-Ag-1Canine CLN8 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0563-Ag-1Bovine CLN8 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0563-Ag-1Equine CLN8 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0563-Ag, GM-Tg-rg-IP0563-Ag, GM-Tg-mg-IP0563-Ag, GM-Tg-cynog-IP0563-Ag,
GM-Tg-felg-IP0563-Ag, GM-Tg-cang-IP0563-Ag, GM-Tg-bovg-IP0563-Ag, GM-Tg-equg-IP0563-Ag-1
Products Name CLN8 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCLN8
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLN8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.