Recombinant multi-species CP8B1/ CYP8B1/ CP8B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP8B1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CYP8B1, gene name: CYP8B1, also named as CP8B, CYP12. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0662-Ag-1Human CYP8B1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0662-Ag-1Rat CYP8B1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0662-Ag-1Mouse CYP8B1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0662-Ag-1Cynomolgus/ Rhesus macaque CYP8B1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0662-Ag-1Feline CYP8B1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0662-Ag-1Canine CYP8B1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0662-Ag-1Bovine CYP8B1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0662-Ag-1Equine CYP8B1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0662-Ag, GM-Tg-rg-IP0662-Ag, GM-Tg-mg-IP0662-Ag, GM-Tg-cynog-IP0662-Ag,
GM-Tg-felg-IP0662-Ag, GM-Tg-cang-IP0662-Ag, GM-Tg-bovg-IP0662-Ag, GM-Tg-equg-IP0662-Ag-1
Products Name CYP8B1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCYP8B1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP8B1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.