Recombinant multi-species DEN1B/ DENND1B/ C1ORF18 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to DENND1B/DENND1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DENND1B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: DENND1B, gene name: DENND1B, also named as C1ORF18, C1orf218, FAM31B. Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0678-Ag-1Human DENND1B proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0678-Ag-1Rat DENND1B proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0678-Ag-1Mouse DENND1B proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0678-Ag-1Cynomolgus/ Rhesus macaque DENND1B proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0678-Ag-1Feline DENND1B proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0678-Ag-1Canine DENND1B proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0678-Ag-1Bovine DENND1B proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0678-Ag-1Equine DENND1B proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0678-Ag, GM-Tg-rg-IP0678-Ag, GM-Tg-mg-IP0678-Ag, GM-Tg-cynog-IP0678-Ag,
GM-Tg-felg-IP0678-Ag, GM-Tg-cang-IP0678-Ag, GM-Tg-bovg-IP0678-Ag, GM-Tg-equg-IP0678-Ag-1
Products Name DENND1B protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameDENND1B
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DENND1B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.