Recombinant multi-species ESPL1/ ESP1/ SEPA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to ESPL1/ESPL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ESPL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ESPL1, gene name: ESPL1, also named as ESP1, SEPA. Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0771-Ag-1Human ESPL1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0771-Ag-1Rat ESPL1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0771-Ag-1Mouse ESPL1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0771-Ag-1Cynomolgus/ Rhesus macaque ESPL1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0771-Ag-1Feline ESPL1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0771-Ag-1Canine ESPL1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0771-Ag-1Bovine ESPL1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0771-Ag-1Equine ESPL1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0771-Ag, GM-Tg-rg-IP0771-Ag, GM-Tg-mg-IP0771-Ag, GM-Tg-cynog-IP0771-Ag,
GM-Tg-felg-IP0771-Ag, GM-Tg-cang-IP0771-Ag, GM-Tg-bovg-IP0771-Ag, GM-Tg-equg-IP0771-Ag-1
Products Name ESPL1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameESPL1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ESPL1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.