Recombinant multi-species FBW12/ FBXW12/ FBXO12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to FBXW12/FBXW12 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FBXW12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: FBXW12, gene name: FBXW12, also named as FBW12, FBXO12, FBXO35. Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0838-Ag-1Human FBXW12 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0838-Ag-1Rat FBXW12 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0838-Ag-1Mouse FBXW12 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0838-Ag-1Cynomolgus/ Rhesus macaque FBXW12 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0838-Ag-1Feline FBXW12 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0838-Ag-1Canine FBXW12 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0838-Ag-1Bovine FBXW12 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0838-Ag-1Equine FBXW12 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-IP0838-Ag, GM-Tg-rg-IP0838-Ag, GM-Tg-mg-IP0838-Ag, GM-Tg-cynog-IP0838-Ag,
GM-Tg-felg-IP0838-Ag, GM-Tg-cang-IP0838-Ag, GM-Tg-bovg-IP0838-Ag, GM-Tg-equg-IP0838-Ag-1
Products Name FBXW12 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameFBXW12
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FBXW12 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.