Recombinant multi-species HTRA2/ MGCA8/ OMI protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to HTRA2/HTRA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HTRA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HTRA2, gene name: HTRA2, also named as MGCA8, OMI, PARK13, PRSS25. This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0992-Ag-1Human HTRA2 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0992-Ag-1Rat HTRA2 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0992-Ag-1Mouse HTRA2 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0992-Ag-1Cynomolgus/ Rhesus macaque HTRA2 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0992-Ag-1Feline HTRA2 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0992-Ag-1Canine HTRA2 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0992-Ag-1Bovine HTRA2 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0992-Ag-1Equine HTRA2 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-IP0992-Ag, GM-Tg-rg-IP0992-Ag, GM-Tg-mg-IP0992-Ag, GM-Tg-cynog-IP0992-Ag,
GM-Tg-felg-IP0992-Ag, GM-Tg-cang-IP0992-Ag, GM-Tg-bovg-IP0992-Ag, GM-Tg-equg-IP0992-Ag-1
Products Name HTRA2 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameHTRA2
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HTRA2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.