Recombinant multi-species LMNA/ CDCD1/ CDDC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LMNA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: LMNA, gene name: LMNA, also named as CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, MADA, PRO1. The protein encoded by this gene is part of the nuclear lamina, a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, May 2022].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-IP1097-Ag-1	Human LMNA protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-IP1097-Ag-1	Rat LMNA protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-IP1097-Ag-1	Mouse LMNA protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-IP1097-Ag-1	Cynomolgus/ Rhesus macaque LMNA protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-IP1097-Ag-1	Feline LMNA protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-IP1097-Ag-1	Canine LMNA protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP1097-Ag-1	Bovine LMNA protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP1097-Ag-1	Equine LMNA protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-IP1097-Ag, GM-Tg-rg-IP1097-Ag, GM-Tg-mg-IP1097-Ag, GM-Tg-cynog-IP1097-Ag, GM-Tg-felg-IP1097-Ag, GM-Tg-cang-IP1097-Ag, GM-Tg-bovg-IP1097-Ag, GM-Tg-equg-IP1097-Ag-1
Products Name	LMNA protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	LMNA
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LMNA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.