Recombinant multi-species MA1B1/ MAN1B1/ ERMAN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to MAN1B1/MAN1B1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAN1B1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: MAN1B1, gene name: MAN1B1, also named as ERMAN1, ERManI, MANA-ER, MRT15. This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP1142-Ag-1Human MAN1B1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP1142-Ag-1Rat MAN1B1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP1142-Ag-1Mouse MAN1B1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP1142-Ag-1Cynomolgus/ Rhesus macaque MAN1B1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP1142-Ag-1Feline MAN1B1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP1142-Ag-1Canine MAN1B1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP1142-Ag-1Bovine MAN1B1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP1142-Ag-1Equine MAN1B1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP1142-Ag, GM-Tg-rg-IP1142-Ag, GM-Tg-mg-IP1142-Ag, GM-Tg-cynog-IP1142-Ag,
GM-Tg-felg-IP1142-Ag, GM-Tg-cang-IP1142-Ag, GM-Tg-bovg-IP1142-Ag, GM-Tg-equg-IP1142-Ag-1
Products Name MAN1B1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameMAN1B1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAN1B1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.