Recombinant multi-species MANEA/ ENDO/ hEndo protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to MANEA/MANEA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MANEA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: MANEA, gene name: MANEA, also named as ENDO, hEndo. N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP1146-Ag-1Human MANEA proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP1146-Ag-1Rat MANEA proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP1146-Ag-1Mouse MANEA proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP1146-Ag-1Cynomolgus/ Rhesus macaque MANEA proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP1146-Ag-1Feline MANEA proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP1146-Ag-1Canine MANEA proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP1146-Ag-1Bovine MANEA proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP1146-Ag-1Equine MANEA proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP1146-Ag, GM-Tg-rg-IP1146-Ag, GM-Tg-mg-IP1146-Ag, GM-Tg-cynog-IP1146-Ag,
GM-Tg-felg-IP1146-Ag, GM-Tg-cang-IP1146-Ag, GM-Tg-bovg-IP1146-Ag, GM-Tg-equg-IP1146-Ag-1
Products Name MANEA protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameMANEA
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MANEA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.