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Recombinant multi-species NAGPA/ APAA/ UCE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Go to NAGPA/NAGPA products collection >>Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NAGPA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: NAGPA, gene name: NAGPA, also named as APAA, UCE. Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. The encoded preproprotein is proteolytically processed by furin to generate the mature enzyme, a homotetramer of two disulfide-linked homodimers. Mutations in this gene are associated with developmental stuttering in human patients. [provided by RefSeq, Oct 2015].
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| Catalog No. | Product Name | Species | Size | Price |
| GM-Tg-hg-IP1233-Ag-1 | Human NAGPA protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-IP1233-Ag-1 | Rat NAGPA protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-IP1233-Ag-1 | Mouse NAGPA protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-IP1233-Ag-1 | Cynomolgus/ Rhesus macaque NAGPA protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-felg-IP1233-Ag-1 | Feline NAGPA protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cang-IP1233-Ag-1 | Canine NAGPA protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-IP1233-Ag-1 | Bovine NAGPA protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-IP1233-Ag-1 | Equine NAGPA protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
| Catalog No. | GM-Tg-hg-IP1233-Ag, GM-Tg-rg-IP1233-Ag, GM-Tg-mg-IP1233-Ag, GM-Tg-cynog-IP1233-Ag, GM-Tg-felg-IP1233-Ag, GM-Tg-cang-IP1233-Ag, GM-Tg-bovg-IP1233-Ag, GM-Tg-equg-IP1233-Ag-1 |
| Products Name | NAGPA protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | NAGPA |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NAGPA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
