Recombinant multi-species AAPK2/ PRKAA2/ AMPK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRKAA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PRKAA2, gene name: PRKAA2, also named as AMPK, AMPK2, AMPKa2, PRKAA. The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-IP1444-Ag-1	Human PRKAA2 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-IP1444-Ag-1	Rat PRKAA2 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-IP1444-Ag-1	Mouse PRKAA2 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-IP1444-Ag-1	Cynomolgus/ Rhesus macaque PRKAA2 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-IP1444-Ag-1	Feline PRKAA2 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-IP1444-Ag-1	Canine PRKAA2 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP1444-Ag-1	Bovine PRKAA2 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP1444-Ag-1	Equine PRKAA2 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-IP1444-Ag, GM-Tg-rg-IP1444-Ag, GM-Tg-mg-IP1444-Ag, GM-Tg-cynog-IP1444-Ag, GM-Tg-felg-IP1444-Ag, GM-Tg-cang-IP1444-Ag, GM-Tg-bovg-IP1444-Ag, GM-Tg-equg-IP1444-Ag-1
Products Name	PRKAA2 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	PRKAA2
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRKAA2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.