Recombinant multi-species TMC8/ EV2/ EVER2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to TMC8/TMC8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMC8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TMC8, gene name: TMC8, also named as EV2, EVER2, EVIN2. Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP1938-Ag-1Human TMC8 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP1938-Ag-1Rat TMC8 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP1938-Ag-1Mouse TMC8 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP1938-Ag-1Cynomolgus/ Rhesus macaque TMC8 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP1938-Ag-1Feline TMC8 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP1938-Ag-1Canine TMC8 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP1938-Ag-1Bovine TMC8 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP1938-Ag-1Equine TMC8 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP1938-Ag, GM-Tg-rg-IP1938-Ag, GM-Tg-mg-IP1938-Ag, GM-Tg-cynog-IP1938-Ag,
GM-Tg-felg-IP1938-Ag, GM-Tg-cang-IP1938-Ag, GM-Tg-bovg-IP1938-Ag, GM-Tg-equg-IP1938-Ag-1
Products Name TMC8 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameTMC8
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMC8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.