Recombinant multi-species TMM43/ TMEM43/ ARVC5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to TMEM43/TMEM43 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMEM43 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TMEM43, gene name: TMEM43, also named as ARVC5, ARVD5, EDMD7, LUMA. This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq, Oct 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP2104-Ag-1Human TMEM43 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP2104-Ag-1Rat TMEM43 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP2104-Ag-1Mouse TMEM43 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP2104-Ag-1Cynomolgus/ Rhesus macaque TMEM43 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP2104-Ag-1Feline TMEM43 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP2104-Ag-1Canine TMEM43 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2104-Ag-1Bovine TMEM43 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2104-Ag-1Equine TMEM43 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP2104-Ag, GM-Tg-rg-IP2104-Ag, GM-Tg-mg-IP2104-Ag, GM-Tg-cynog-IP2104-Ag,
GM-Tg-felg-IP2104-Ag, GM-Tg-cang-IP2104-Ag, GM-Tg-bovg-IP2104-Ag, GM-Tg-equg-IP2104-Ag-1
Products Name TMEM43 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameTMEM43
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMEM43 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.