Recombinant multi-species TSC2/ LAM/ PPP1R160 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to TSC2/TSC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TSC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TSC2, gene name: TSC2, also named as LAM, PPP1R160, TSC4. This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis. [provided by RefSeq, May 2022].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP2180-Ag-1Human TSC2 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP2180-Ag-1Rat TSC2 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP2180-Ag-1Mouse TSC2 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP2180-Ag-1Cynomolgus/ Rhesus macaque TSC2 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP2180-Ag-1Feline TSC2 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP2180-Ag-1Canine TSC2 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2180-Ag-1Bovine TSC2 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2180-Ag-1Equine TSC2 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP2180-Ag, GM-Tg-rg-IP2180-Ag, GM-Tg-mg-IP2180-Ag, GM-Tg-cynog-IP2180-Ag,
GM-Tg-felg-IP2180-Ag, GM-Tg-cang-IP2180-Ag, GM-Tg-bovg-IP2180-Ag, GM-Tg-equg-IP2180-Ag-1
Products Name TSC2 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameTSC2
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TSC2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.