Recombinant multi-species LOXE3/ ALOXE3/ ARCI3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to ALOXE3/ALOXE3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALOXE3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ALOXE3, gene name: ALOXE3, also named as ARCI3, E-LOX, eLOX-3, eLOX3. This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP2336-Ag-1Human ALOXE3 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP2336-Ag-1Rat ALOXE3 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP2336-Ag-1Mouse ALOXE3 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP2336-Ag-1Cynomolgus/ Rhesus macaque ALOXE3 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP2336-Ag-1Feline ALOXE3 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP2336-Ag-1Canine ALOXE3 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2336-Ag-1Bovine ALOXE3 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2336-Ag-1Equine ALOXE3 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP2336-Ag, GM-Tg-rg-IP2336-Ag, GM-Tg-mg-IP2336-Ag, GM-Tg-cynog-IP2336-Ag,
GM-Tg-felg-IP2336-Ag, GM-Tg-cang-IP2336-Ag, GM-Tg-bovg-IP2336-Ag, GM-Tg-equg-IP2336-Ag-1
Products Name ALOXE3 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameALOXE3
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALOXE3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.