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Recombinant multi-species ELOC/ SIII/ TCEB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Go to ELOC/ELOC products collection >>Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ELOC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: ELOC, gene name: ELOC, also named as SIII, TCEB1. This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011].
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| Catalog No. | Product Name | Species | Size | Price |
| GM-Tg-hg-IP2473-Ag-1 | Human ELOC protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-IP2473-Ag-1 | Rat ELOC protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-IP2473-Ag-1 | Mouse ELOC protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-IP2473-Ag-1 | Cynomolgus/ Rhesus macaque ELOC protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-felg-IP2473-Ag-1 | Feline ELOC protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cang-IP2473-Ag-1 | Canine ELOC protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-IP2473-Ag-1 | Bovine ELOC protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-IP2473-Ag-1 | Equine ELOC protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
| Catalog No. | GM-Tg-hg-IP2473-Ag, GM-Tg-rg-IP2473-Ag, GM-Tg-mg-IP2473-Ag, GM-Tg-cynog-IP2473-Ag, GM-Tg-felg-IP2473-Ag, GM-Tg-cang-IP2473-Ag, GM-Tg-bovg-IP2473-Ag, GM-Tg-equg-IP2473-Ag-1 |
| Products Name | ELOC protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ELOC |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ELOC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
