Recombinant multi-species IKZF3/ AIO/ AIOLOS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to IKZF3/IKZF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IKZF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IKZF3, gene name: IKZF3, also named as AIO, AIOLOS, ZNFN1A3. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP2547-Ag-1Human IKZF3 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP2547-Ag-1Rat IKZF3 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP2547-Ag-1Mouse IKZF3 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP2547-Ag-1Cynomolgus/ Rhesus macaque IKZF3 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP2547-Ag-1Feline IKZF3 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP2547-Ag-1Canine IKZF3 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2547-Ag-1Bovine IKZF3 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2547-Ag-1Equine IKZF3 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP2547-Ag, GM-Tg-rg-IP2547-Ag, GM-Tg-mg-IP2547-Ag, GM-Tg-cynog-IP2547-Ag,
GM-Tg-felg-IP2547-Ag, GM-Tg-cang-IP2547-Ag, GM-Tg-bovg-IP2547-Ag, GM-Tg-equg-IP2547-Ag-1
Products Name IKZF3 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameIKZF3
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IKZF3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.