Recombinant multi-species NKX28/ NKX2-8/ NKX2.8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to NKX2-8/NKX2-8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NKX2-8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: NKX2-8, gene name: NKX2-8, also named as NKX2.8, NKX2H, Nkx2-9. The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP2628-Ag-1Human NKX2-8 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP2628-Ag-1Rat NKX2-8 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP2628-Ag-1Mouse NKX2-8 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP2628-Ag-1Cynomolgus/ Rhesus macaque NKX2-8 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP2628-Ag-1Feline NKX2-8 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP2628-Ag-1Canine NKX2-8 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2628-Ag-1Bovine NKX2-8 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2628-Ag-1Equine NKX2-8 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP2628-Ag, GM-Tg-rg-IP2628-Ag, GM-Tg-mg-IP2628-Ag, GM-Tg-cynog-IP2628-Ag,
GM-Tg-felg-IP2628-Ag, GM-Tg-cang-IP2628-Ag, GM-Tg-bovg-IP2628-Ag, GM-Tg-equg-IP2628-Ag-1
Products Name NKX2-8 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameNKX2-8
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NKX2-8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.