Recombinant multi-species A2MG/ A2M/ A2MD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine A2M protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: A2M, gene name: A2M, also named as A2MD, CPAMD5, FWP007, S863-7. The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE0001-Ag-1	Human A2M protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE0001-Ag-1	Rat A2M protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE0001-Ag-1	Mouse A2M protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE0001-Ag-1	Cynomolgus/ Rhesus macaque A2M protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE0001-Ag-1	Feline A2M protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE0001-Ag-1	Canine A2M protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE0001-Ag-1	Bovine A2M protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE0001-Ag-1	Equine A2M protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE0001-Ag, GM-Tg-rg-SE0001-Ag, GM-Tg-mg-SE0001-Ag, GM-Tg-cynog-SE0001-Ag, GM-Tg-felg-SE0001-Ag, GM-Tg-cang-SE0001-Ag, GM-Tg-bovg-SE0001-Ag, GM-Tg-equg-SE0001-Ag-1
Products Name	A2M protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	A2M
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine A2M protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.