Recombinant multi-species ASPN/ OS3/ PLAP-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to ASPN/ASPN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASPN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ASPN, gene name: ASPN, also named as OS3, PLAP-1, PLAP1, SLRR1C. This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.[provided by RefSeq, Jul 2014].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0032-Ag-1Human ASPN proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0032-Ag-1Rat ASPN proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0032-Ag-1Mouse ASPN proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0032-Ag-1Cynomolgus/ Rhesus macaque ASPN proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0032-Ag-1Feline ASPN proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0032-Ag-1Canine ASPN proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0032-Ag-1Bovine ASPN proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0032-Ag-1Equine ASPN proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-SE0032-Ag, GM-Tg-rg-SE0032-Ag, GM-Tg-mg-SE0032-Ag, GM-Tg-cynog-SE0032-Ag,
GM-Tg-felg-SE0032-Ag, GM-Tg-cang-SE0032-Ag, GM-Tg-bovg-SE0032-Ag, GM-Tg-equg-SE0032-Ag-1
Products Name ASPN protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameASPN
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASPN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.