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Recombinant multi-species DNS2B/ DNASE2B/ DLAD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Go to DNASE2B/DNASE2B products collection >>Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNASE2B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: DNASE2B, gene name: DNASE2B, also named as DLAD. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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| Catalog No. | Product Name | Species | Size | Price |
| GM-Tg-hg-SE0161-Ag-1 | Human DNASE2B protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0161-Ag-1 | Rat DNASE2B protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0161-Ag-1 | Mouse DNASE2B protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0161-Ag-1 | Cynomolgus/ Rhesus macaque DNASE2B protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-felg-SE0161-Ag-1 | Feline DNASE2B protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cang-SE0161-Ag-1 | Canine DNASE2B protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-SE0161-Ag-1 | Bovine DNASE2B protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-SE0161-Ag-1 | Equine DNASE2B protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
| Catalog No. | GM-Tg-hg-SE0161-Ag, GM-Tg-rg-SE0161-Ag, GM-Tg-mg-SE0161-Ag, GM-Tg-cynog-SE0161-Ag, GM-Tg-felg-SE0161-Ag, GM-Tg-cang-SE0161-Ag, GM-Tg-bovg-SE0161-Ag, GM-Tg-equg-SE0161-Ag-1 |
| Products Name | DNASE2B protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DNASE2B |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNASE2B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
