Recombinant multi-species DSE/ DS-epi1P/ DSEPI protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to DSE/DSE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DSE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: DSE, gene name: DSE, also named as DS-epi1P, DSEPI, EDSMC2, SART-2, SART2, DSE. The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0163-Ag-1Human DSE proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0163-Ag-1Rat DSE proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0163-Ag-1Mouse DSE proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0163-Ag-1Cynomolgus/ Rhesus macaque DSE proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0163-Ag-1Feline DSE proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0163-Ag-1Canine DSE proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0163-Ag-1Bovine DSE proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0163-Ag-1Equine DSE proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-SE0163-Ag, GM-Tg-rg-SE0163-Ag, GM-Tg-mg-SE0163-Ag, GM-Tg-cynog-SE0163-Ag,
GM-Tg-felg-SE0163-Ag, GM-Tg-cang-SE0163-Ag, GM-Tg-bovg-SE0163-Ag, GM-Tg-equg-SE0163-Ag-1
Products Name DSE protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameDSE
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DSE protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.