Recombinant multi-species GRAH/ GZMH/ CCP-X protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to GZMH/GZMH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GZMH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: GZMH, gene name: GZMH, also named as CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2. This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0253-Ag-1Human GZMH proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0253-Ag-1Rat GZMH proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0253-Ag-1Mouse GZMH proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0253-Ag-1Cynomolgus/ Rhesus macaque GZMH proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0253-Ag-1Feline GZMH proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0253-Ag-1Canine GZMH proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0253-Ag-1Bovine GZMH proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0253-Ag-1Equine GZMH proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-SE0253-Ag, GM-Tg-rg-SE0253-Ag, GM-Tg-mg-SE0253-Ag, GM-Tg-cynog-SE0253-Ag,
GM-Tg-felg-SE0253-Ag, GM-Tg-cang-SE0253-Ag, GM-Tg-bovg-SE0253-Ag, GM-Tg-equg-SE0253-Ag-1
Products Name GZMH protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameGZMH
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GZMH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.