Recombinant multi-species A2ML1/ CPAMD9/ OMS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine A2ML1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: A2ML1, gene name: A2ML1, also named as CPAMD9, OMS, p170. This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE0631-Ag-1	Human A2ML1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE0631-Ag-1	Rat A2ML1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE0631-Ag-1	Mouse A2ML1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE0631-Ag-1	Cynomolgus/ Rhesus macaque A2ML1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE0631-Ag-1	Feline A2ML1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE0631-Ag-1	Canine A2ML1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE0631-Ag-1	Bovine A2ML1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE0631-Ag-1	Equine A2ML1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE0631-Ag, GM-Tg-rg-SE0631-Ag, GM-Tg-mg-SE0631-Ag, GM-Tg-cynog-SE0631-Ag, GM-Tg-felg-SE0631-Ag, GM-Tg-cang-SE0631-Ag, GM-Tg-bovg-SE0631-Ag, GM-Tg-equg-SE0631-Ag-1
Products Name	A2ML1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	A2ML1
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine A2ML1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.