Recombinant multi-species ARTN/ ART/ ENOVIN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARTN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ARTN, gene name: ARTN, also named as ART, ENOVIN, EVN, NBN. This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE0680-Ag-1	Human ARTN protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE0680-Ag-1	Rat ARTN protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE0680-Ag-1	Mouse ARTN protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE0680-Ag-1	Cynomolgus/ Rhesus macaque ARTN protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE0680-Ag-1	Feline ARTN protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE0680-Ag-1	Canine ARTN protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE0680-Ag-1	Bovine ARTN protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE0680-Ag-1	Equine ARTN protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE0680-Ag, GM-Tg-rg-SE0680-Ag, GM-Tg-mg-SE0680-Ag, GM-Tg-cynog-SE0680-Ag, GM-Tg-felg-SE0680-Ag, GM-Tg-cang-SE0680-Ag, GM-Tg-bovg-SE0680-Ag, GM-Tg-equg-SE0680-Ag-1
Products Name	ARTN protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	ARTN
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARTN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.